|Season 02, Number 01|
|Air date||November 17, 2010|
|Written by||Matt Miller|
|Directed by||Steve Boyum|
|U.S. viewers||6.59 million|
|U.S. ratings|| 4.0/7 HH|
| Location: San Francisco, California|
|Technology billionaire, philanthropist|
"The Wife's Tale"
Ilsa Pucci is the first episode of the second season of Human Target.
Chance and Guerrero put a plan in motion to rescue Winston, after he was kidnapped in last season's finale. Two women join up with the team – billionaire philanthropist Ilsa Pucci, who fears for her life after the mysterious death of her husband, and Ames, a young master (mistress?) thief who inadvertently becomes entangled in the plot to murder the team's latest client, and takes cooperation over the close attentions of Guerrero, or others like him.
- Rick Hoffman as Shelly
- Janet Montgomery as Ames
- Timothy Omundson as Interrogator
- Tahmoh Penikett as Pete
- David Ali as Pakistani Man
- Lars Anderson as Security Guard (Geneva)
- George Daburaas as Lars
- Michael Jonsson as Security Guard (SF)
- Jarod Joseph as Larry
- Thai-Hoa Le as Monk #2
- Ecstasia Sanders as Denise
- Chhultim Sherpa as Monk #1
- This episode is erroneously listed as Episode 13 of Season 1 on the DCUniverse streaming service.